Dexmedetomidine to facilitate drug withdrawal

  The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects

  Dexmedetomidine-induced sedation in volunteers decreases regional and global cerebral blood flow.

  Assessment of the sedative effects of dexmedetomidine, an alpha 2-adrenoceptor agonist, with analysis of saccadic eye movements.

  Dexmedetomidine reduces intraocular pressure, intubation responses and anaesthetic requirements in patients undergoing ophthalmic surgery.

  Dexmedetomidine decreases cerebral blood flow velocity in humans.

  Comparison of dexmedetomidine and midazolam sedation and antagonism of dexmedetomidine with atipamezole.

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